GeneArt Gene Synthesis and Services

GeneArt Gene Synthesis is a reliable and cost-effective method for obtaining customized DNA constructs with 100% sequence accuracy.

GeneArt Gene Synthesis is a reliable and cost-effective method for obtaining customized DNA constructs with 100% sequence accuracy. Our GeneOptimizer algorithm utilizes a multifactorial approach (up to 20 parameters) beyond just traditional codon optimization to significantly improve protein expression when it comes wild-type protein.

The GeneArt Instant Designer ordering tool provides a powerful yet simple approach to ordering with both Prime and Value Gene Synthesis Services to tackle everything from simple to complex sequences.

  • GeneArt Strings DNA Fragments: Synthesis of linear dsDNA fragments up to 3 kb. 
  • GeneArt Gene Synthesis: Synthesis of DNA of interest, cloning of DNA into standard vector or expression vector of choice (ready to use)
  • GeneArt Genes-to-Proteins: Expression and purification of proteins from mammalian cells as all-in-one solution, starting from only the electronic nucleotide sequence

 GeneArt Strings DNA Fragments:

  • Gene optimization function
  • No physical template required
  • Reliable technology available to clone or assemble your complete gene (e.g., GeneArt™ Type IIs Assembly Kits)
  • Affordable and fast (5 working days)
  • Gene design flexibility
  • Delivery amount (lyophilized DNA): ≥ 200 ng

 GeneArt Gene Synthesis

  • Full gene optimization
  • No physical template required
  • Synthesis of complex sequences (e.g., high/low GC content)
  • Downstream services available
  • All custom synthesized genes are sequenced as part of our ISO 9001:2015–certified quality management system; we only ship constructs with exact sequence agreement.
  • Convenient ordering
  • Full sequence design flexibility
  • Synthesis of large sequences (<100 kb)
  • Delivery amount (lyophilized DNA): 5 µg plasmid DNA

 GeneArt Genes-to-Proteins: 

  • Reliable and advanced expression systems (FreeStyle™ 293, CHO, and Expi293™)
  • Expression-optimized genes
  • Expression scales from 30 mL to 25 L
  • No physical template required
  • All production steps from a single-source provider
  • Experienced scientists
  • Target proteins testing by Coomassie staining, SDS-PAGE and Western Blot 

Characterisitcs  
GeneArt Strings DNA Fragments
Length (base pairs) 200 – to 3,000
Accuracy (error per base) less than 1 in 5,000
GC content 30 – 70% GC
Total reliability 95%
Delivery amount
(lyophilized DNA)
Minimum > 200 ng
Average 900 ng
GeneArt Gene Synthesis
Length (base pairs) 100 - 12000
QC sequencing method
  • Sanger Sequencing
  • Next Gen Sequencing
Express cloning Yes
GeneArt Genes-to-Proteins 
Mammalian expression systems
  • Invitrogen FreeStyle CHO-S cells
  • Invitrogen FreeStyle 293-F cells
  • Gibco Expi293 F cells
  • Gibco ExpiCHO-S cells
Insect expression system
  • Invitrogen Bac-to-Bac expression system
Expression scales
  • 30 mL to 25 L
  • Shaker and WAVE bag–based cell culture
Purification methods
  • Affinity chromatography
  • Size exclusion chromatography (SEC)
  • Ion exchange chromatography (IEX)
Affinity tags
  • His-Tag
  • Fc-Tag (Protein A/G)
  • Strep-Tag
  • GST-Tag
  • Other, upon request
Additional options
  • 2nd column purification
  • Tag cleavage
  • Analytical SEC (HPLC)
  • Customized buffer
  • Endotoxin determination
  • Aliquot service
  • Concentration adjustment
  • Titer determination in culture supernatant (antibodies)
  • Other, upon request

Please contact us for more information!

CRISPR Cas9 Technology

CRISPR Cas9 Technology

The transformative CRISPR-Cas9 technology is revolutionizing the field of genome editing. Able to achieve highly flexible and specific targeting, the CRISPR-Cas9 system can be modified and redirected to become a powerful tool for genome editing in broad applications such as stem cell engineering, gene therapy, tissue and animal disease models, and engineering disease-resistant transgenic plants. We've put together a collection of resources that we hope will give you the confidence to get started and to continuously improve your research.

Collibri™ NGS Library Prep Kit

Collibri™ NGS Library Prep Kit

Product name: Collibri NGS Library Pre Kit

Manufacture: Invitrogen/ Thermo Fisher Scientific

Authorized distributor