Recombinant Human Interleukin 6 (IL6) is a bioactive protein intended for use in cell culture applications. IL6 is a pleotropic cytokine involved in several cellular processes including inflammation, hematopoeisis, and immune response. The lyophilized, E. coli-expressed IL6 Recombinant Human is verified for activity through dose-dependent proliferation of mouse B9 cells.

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High Purity
To help verify that GIBCO® Recombinant growth factors are of the highest quality, each protein is analyzed for purity, along with structural homogeneity, to help ensure a biologically active protein. The purity of each GIBCO® recombinant growth factor is verified by SDS-PAGE to be over 95% pure and to have endotoxin levels below 0.1 ng/μg.

High Biological Activity
All GIBCO® Recombinant growth factors are verified for activity. Each lot has its own ED50 determined using an activity assay based on a specific function of the growth factor. The activity of our IL6 Recombinant Human growth factor is determined by the dose-dependent proliferation of mouse B9 cells to have an ED50 range of 0.008–0.02 ng/mL (specific activity: 1.25 × 10^8–5.0 × 10^7 units/mg). Optimal concentration for individual applications should be determined by a dose response assay.